Nicholas Wheeler, Oregon State University; David Harry, Oregon State University; Heather L. Merk, The Ohio State University
Development of association genetics, sometimes called association mapping or LD mapping, was driven by human geneticists seeking to characterize the hereditary basis of disease. The approach was made possible by the discovery of literally millions of SNPs in the human genome and the development of high throughput platforms that provide genotypes simultaneously for hundreds of thousands of SNPs. The approach was rapidly adopted by plant and animal breeders who envisioned its application for marker-assisted selection (MAS). The forest genetics community initiated association studies in 2000 and has contributed significantly to the development of high throughput genotyping capacity for the plant community.
You can also watch the video on YouTube.
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Cite This Learning Module
- Wheeler, N., and D. Harry. Association genetics [Online]. Genomics in Tree Breeding and Forest Ecosystem Management, Conifer Translational Genomics Network. eXtension Foundation. Available at: https://plant-breeding-genomics.extension.org/association-genetics:-conifer-genomics-module-11/ (verified April 22, 2013).
- Nicholas Wheeler and David Harry developed the learning module content.
- Heather Merk developed the webpage.
Support for the Conifer Translational Genomics Network project and the development of the teaching modules hosted here was provided by the USDA/NRI CSREES Coordinated Agricultural Project (CAP) Award # 2007-55300-18603, the USDA/NIFA AFRI Applied Plant Genomics CAP Award #2009-85606-05680 and the USDA Forest Service. Development of this page was supported in part by the National Institute of Food and Agriculture (NIFA) Solanaceae Coordinated Agricultural Project, agreement 2009-85606-05673, administered by Michigan State University. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the United States Department of Agriculture.
Association_Genetics.pdf (1.3 MB)